2022 Baseball Schedule |
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| Day | Date | Opponent | Location | Time/Result | Record |
| Fri | 2/18 | Indiana | Clemson, SC | 4:00PM | |
| Sat | 2/19 | Indiana | Clemson, SC | 3:00PM | |
| Sun | 2/20 | Indiana | Clemson, SC | 1:00PM | |
| Tue | 2/22 | College of Charleston | Clemson, SC | 4:00PM | |
| Fri | 2/25 | Hartford | Clemson, SC | 4:00PM | |
| Sat | 2/26 | Hartford | Clemson, SC | 3:00PM | |
| Sun | 2/27 | Hartford | Clemson, SC | 1:00 PM | |
| Tue | 3/1 | USC Upstate | Greenville SC | TBA | |
| Fri | 3/4 | South Carolina | Columbia, SC | TBA | |
| Sat | 3/5 | South Carolina | Columbia, SC | 4:00PM | |
| Sun | 3/6 | South Carolina | Clemson, SC | 2:00PM | |
| Tue | 3/8 | East Tenn State | Clemson, SC | 4:00PM | |
| Tue | 3/9 | Michigan St | Greenville, SC | TBA | |
| Fri | 3/11 | Northeastern | Clemson, SC | 4:00PM | |
| Sat | 3/12 | Northeastern | Clemson, SC | 3:00PM | |
| Sun | 3/13 | Northeastern | Clemson, SC | 1:00PM | |
| Tue | 3/15 | Georgia State | Clemson, SC | 6:00PM | |
| Fri | 3/18 | Miami | Clemson, SC | 6:00PM | |
| Sat | 3/19 | Miami | Clemson, SC | 3:00PM | |
| Sun | 3/20 | Miami | Clemson, SC | 1:00PM | |
| Tue | 3/22 | Coastal Carolina | Clemson, SC | 6:00 PM | |
| Wed | 3/22 | Winthrop | Clemson, SC | 6:00 PM | |
| Fri | 3/25 | Pitt | Clemson, SC | TBA | |
| Sat | 3/26 | Pitt | Clemson, SC | TBA | |
| Sun | 3/27 | Pitt | Clemson, SC | TBA | |
| Tue | 3/29 | Winthrop | Rock Hill, SC | TBA | |
| Fri | 4/1 | North Carolina State | Clemson, SC | 6:00 PM | |
| Sat | 4/2 | North Carolina State | Clemson, SC | 3:00 PM | |
| Sun | 4/3 | North Carolina State | Clemson, SC | 1:00 PM | |
| Tue | 4/5 | Georgia | Clemson, SC | 6:00 PM | |
| Fri | 4/8 | Notre Dame | South Bend | TBA | |
| Sat | 4/9 | Notre Dame | South Bend | TBA | |
| Sun | 4/10 | Notre Dame | South Bend | TBA | |
| Tue | 4/12 | USC Upstate | Clemson, SC | 6:00PM | |
| Fri | 4/15 | Wake Forest | Winston-Salem | TBA | |
| Sat | 4/16 | Wake Forest | Winston-Salem | TBA | |
| Sun | 4/17 | Wake Forest | Winston-Salem | TBA | |
| Tue | 4/19 | Georgia | Athens, GA | TBA | |
| Fri | 4/22 | Florida State | Clemson, SC | 6:00PM | |
| Sat | 4/23 | Florida State | Clemson, SC | 3:00PM | |
| Sun | 4/24 | Florida State | Clemson, SC | 1:00PM | |
| Tue | 4/26 | Presbyterian | Clemson, SC | 6:00PM | |
| Fri | 4/29 | Louisville * | Louisville | TBA | |
| Sat | 4/30 | Louisville * | Louisville | TBA | |
| Sun | 5/1 | Louisville * | Louisville | TBA | |
| Fri | 5/6 | Georgia Tech * | Clemson, SC | 6:00PM | |
| Sat | 5/7 | Georgia Tech * | Clemson, SC | 3:00PM | |
| Sun | 5/8 | Georgia Tech * | Clemson, SC | 1:00PM | |
| Sat | 5/13 | Virginia | Charlottesville | 6:00PM | |
| Sat | 5/14 | Virginia | Charlottesville | 2:00PM | |
| Sun | 5/15 | Virginia | Charlottesville | 1:00PM | |
| Tue | 5/17 | Coastal | Conway, SC | 1:00PM | |
| Thu | 5/19 | Boston College | Clemson, SC | 6:00PM | |
| Fri | 5/20 | Boston College | Clemson, SC | 6:00PM | |
| Sat | 5/21 | Boston College | Clemson, SC | 1:00PM | |
| 5/20-25 | ACC Baseball Tournament | TBA | TBA | ||
| * | ACC Regular-Season Game | ||||
| % | Fluor Field, Greenville, SC | ||||
